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1.
JCPSP-Journal of the College of Physicians and Surgeons Pakistan. 2018; 28 (11): 829-833
in English | IMEMR | ID: emr-205208

ABSTRACT

Objective: to determine the diagnostic accuracy of contrast enhanced computed tomography [CECT] of head and neck in detecting adjacent bone invasion due to squamous cell carcinoma of buccal mucosa using histopathology as gold standard


Study Design: cross sectional / descriptive study


Place and Duration of Study: department of Radiology, Dow Medical College, Civil Hospital, Karachi, from September 2015 to October 2016


Methodology: a total of 116 patients clinically suspected of oral cavity squamous cell carcinoma [OCSCC] involving buccal mucosa was included. After taking proper history, all these patients referred to Radiology Department for contrast enhanced contiguous thin slice sections of 3-5 mm the primary site of the lesion prior to surgery. Reconstruction of all images done by using bone algorithm. The diagnostic accuracy of CECT was analysed against the gold standard of histopathology. Statistical analyses were carried out by using SPSS 21. Mean +/- SD were calculated for quantitative variable like age. For qualitative variables, frequencies and percentages were calculated. Sensitivity, specificity, positive predictive value, negative predictive value, and diagnostic accuracy were computed for CECT, taking histopathology as gold standard


Results: eighty-three male [71%] and 33 female [28%] patients. Mean age was 46.66 +/- 10.77 years. Mean duration of sign and symptoms was 3.47 +/- 1.54 months. Sensitivity, specificity, PPV, NPV and accuracy were 69.2%, 78.4%, and 80.4%, 66.7% and 73.3%, respectively


Conclusion: CECT is a reliable technique for detecting adjacent bone invasion due to squamous cell carcinoma of buccal mucosa by using 3-5 mm thin-section CT reconstructed with bone algorithm

2.
Pakistan Journal of Otolaryngology-Head and Neck Surgery. 2012; 28 (2): 53-55
in English | IMEMR | ID: emr-161036

ABSTRACT

Chronic Headache is one of the common visiting symptoms in outpatient department. Amongst various investigations advised by the concerned medical practioner, . X.Ray P.N.S, occipitomental view or water's view is the most common and routine investigation. It is the most commonest radiological investigation because of easy availability of radiographic equipment, low cost and even free service available in public sector Hospitals. To determine the cause of chronic headache after viewing occipitomental view [OM] for para nasal sinuses [PNS] with history of more than one month of duration and to know that this plain radiograph is beneficial for diagnosis. Observational study. Department of Radiology. Civil Hospital Karachi. This study was conducted from October 2010 - December 2010 [3 month] in the Department of Radiology, Civil Hospital Karachi. All patients with symptom of headache of more than one month duration over the age of 18 years were included with conventional radiograph. Patients of less than 18 years of age were excluded from this study. Among 50 patient, 32 [64%] were males and 18 [36%] were females. Out of 25 [50% patients who were diagnosed as sinusitis. 17 [34%] were males and 08 [16%] were females. Pansinusitis was also detected in 13 cases [26%], 07 were males [14%] and 06 were females [12%]. Maxillary sinusitis was also found as a cause of chronic headache. This may be unilateral or bilateral. 10 [20%] cases were detected as maxillary sinusitis. Amongst them 5 [10%] were male and 5 [10%]were females. 3 cases [6%] were detected as bilateral maxillary sinusitis. 2 cases [4%]. were also having mucosal thickening and edema in frontal sinuses. One of the cause of Headache is deflected nasal septum [DNS]. In this study 5 [10%] patient were diagnosed as a case of DNS. Plain film studies ofparanasal sinuses, occipitomental view is the most frequent initial / primary imaging study advised because of its comparatively low cost, frequent availability, low radiation dose and easy to perform entity.. Although, CT Scan ofparanasal sinus is preferred choice especially when Functional Endoscopic Sinus Surgery [FESS] is planned

3.
JLUMHS-Journal of the Liaquat University of Medical Health Sciences. 2010; 9 (1): 12-16
in English | IMEMR | ID: emr-197285

ABSTRACT

Objective: To determine the use of breast imaging in patients with localised or diffuse pain in the breast, in the absence of palpable lump or nipple discharge


Design: Descriptive study


Setting: This study was conducted at Radiology Department of Civil Hospital and Dow University of Health Sciences Karachi from October 2007 to September 2008


Patients and Methods: Patients referred for radiological examination of breast[s] in which either mammography or ultrasound or both done were included. Inclusion criteria was pain in the breast present in women between the ages of 15-65 years. Exclusion criteria included palpable lump, and nipple discharge, patients with a history of breast cancer, or breast augmentation. Mammography was done in those who were above 35 years whereas the ultrasound was carried out in every patient with mastalgia. Main outcome measure was presence of the abnormal radiological findings. Findings were categorized in BIRADS terms. Statistical analysis was done for descriptive statistics. Mean +/- SD of age, numbers and percentage calculation for normal and abnormal findings were carried out


Results: Among the 175 subjects, pain was unilateral in 136 [77.5%] and bilateral in 39 [22.8%] patients. The mean age was 40 +/- 5 years [range 15-65 years]. Ninety-five [54.2%] women belonged to premenopausal or perimenopausal age group. The imaging findings were normal/negative in 114 [65.1%], benign in 43 [24.5%], probably benign in 12 [6.8%], suspicious in 04 [2.2%], and malignant in 02 [1.1%]


Conclusions: No abnormality was found in the painful area in majority of patients. A marked number of patients with benign or probably benign had pain in breast while probable or definite malignant disease was uncommon. Breast imaging in women who present with pain alone provides reassurance

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